相关实验视频
Updated: May 20, 2025

Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation
Published on: January 28, 2021
心脏保护性营养计划对二次心血管疾病预防中的阿波利波蛋白和脂质的影响
Aline Marcadenti1,2,3, Josefina Bressan4, Annie Seixas Bello Moreira5
1Instituto de Pesquisa Hcor, São Paulo, SP, Brasil.
巴西BALANCE计划改善了健康饮食的坚持,但并没有显著改变心血管患者的阿波利波蛋白水平. 然而,它确实在三年内降低了总和非HDL胆固醇.
科学领域:
- 预防心血管疾病预防心血管疾病
- 营养科学 营养科学
- 脂质新陈代谢 脂质新陈代谢
背景情况:
- 二次性心血管预防需要有效的生活方式干预.
- 营养计划在控制心血管风险因素方面发挥着至关重要的作用.
- 脂蛋白和脂质生物标志物是心血管健康的关键指标.
研究的目的:
- 评估巴西心脏保护营养计划 (BALANCE计划) 对阿波利波蛋白和脂质生物标志物的三年影响.
- 评估BALANCE计划在二次心血管预防中的有效性.
主要方法:
- 对276名先前患有心血管疾病的患者 (≥45岁) 的探索性分析.
- 随机对照试验比较BALANCE计划 (干预) 与传统的营养建议 (控制) 在三年内.
- 测量包括临床数据,人体测量,食物摄入量,血阿波利波蛋白和脂质配置文件;依从性使用BALANCE饮食指数进行跟踪.
主要成果:
- 更高的遵守平衡计划,由增加水果,蔬菜,豆类和低脂肪乳制品的摄入量驱动.
- 干预组和对照组之间血阿波利波蛋白水平没有显著差异.
- 与对照组相比,BALANCE组的总胆固醇和非HDL胆固醇显著降低.
结论:
- 在BALANCE计划中显示了很高的坚持,但在三年内并没有显著改变血阿波利波蛋白度.
- 尽管阿波利波蛋白没有变化,但该计划导致总胆固醇和非高密度胆固醇显著降低.
- 这些发现表明,BALANCE计划在二次心血管预防中对特定脂质标记物的潜在益处.
更多相关视频
09:15Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
Published on: November 10, 2017
07:29Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
相关概念视频
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Lipid-derived Compounds in the Human Body
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System