揭示全球研究前沿的除酶和免疫疗法:一项文献计量研究
Xia Chen1, Yang Qin2, Jinfeng Gan3,4
1Department of Geriatrics, Affiliated Hospital of Guilin Medical University, Guilin, China.
Human vaccines & immunotherapeutics
|March 25, 2025
概括
脱化酶 (DUB) 在癌症免疫疗法中至关重要,它会影响瘤的微环境. 自2020年以来,对DUB和免疫疗法的研究急剧增加,揭示了关键趋势和未来方向.
科学领域:
- 生物化学 生物化学
- 免疫学 免疫学 免疫学
- 在瘤学瘤学.
背景情况:
- 脱化酶 (DUBs) 是关键的蛋白质修饰酶,参与癌症的发病.
- DUBs通过调节免疫细胞功能和信号通路,显著影响瘤免疫微环境.
- 在癌症免疫治疗中DUBs的作用是一个新兴的科学兴趣的新兴领域.
研究的目的:
- 进行对DUB和免疫治疗研究的文献分析.
- 确定这一领域的关键研究热点,趋势和新兴前沿.
- 为未来的基于DUB的免疫疗法研究和战略开发提供基础.
主要方法:
- 从科学网数据库中对2014-2024年出版物的图书统计分析.
- 使用CiteSpace,VOSviewer和R的Bibliometrix包进行数据分析和可视化.
- 分析了出版成果,国家/机构的贡献,作者影响,期刊引用和关键词的共同出现.
主要成果:
- 总共有321篇文章被检索,在2020年之后的出版物显著增加.
- 中国在出版量方面处于领先地位,而美国则表现出最具影响力.
- 关键的研究热点包括DUB表达,免疫治疗,无处不在,降解和癌症.
结论:
- 图书统计分析突出了DUB在癌症免疫治疗中的日益重要和研究趋势.
- 确定了关键参与者和研究主题,为该领域的发展轨迹提供了洞察力.
- 研究结果为未来的研究和开发新的DUB向免疫疗法提供了战略指导.
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