Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Pneumonia I: Introduction01:30

Pneumonia I: Introduction

1.5K
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
1.5K
Pneumonia IV: Management01:28

Pneumonia IV: Management

1.2K
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
1.2K
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

88
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
88
Viral Meningitis01:18

Viral Meningitis

196
Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
196
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

101
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
101
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

23
Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
23

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

ATG9A is an essential host factor for parechovirus RNA replication.

Journal of virology·2026
Same author

Natural killer cells and IFN-γ protect against liver injury during HAV infection in mice.

Journal of virology·2025
Same author

Heat shock protein 90 chaperone activity is required for hepatitis A virus replication.

Journal of virology·2025
Same author

Noncanonical Poly(A) Polymerase TENT4 Drives Expression of Subgenomic Hepatitis A Virus RNAs in Infected Cells.

Viruses·2025
Same author

Hepatovirus translation requires PDGFA-associated protein 1, an eIF4E-binding protein regulating endoplasmic reticulum stress responses.

Science advances·2024
Same author

A self-amplifying RNA vaccine prevents enterovirus D68 infection and disease in preclinical models.

Science translational medicine·2024

相关实验视频

Updated: Apr 30, 2026

Efficient Recombinant Parvovirus Production with the Help of Adenovirus-derived Systems
13:47

Efficient Recombinant Parvovirus Production with the Help of Adenovirus-derived Systems

Published on: April 23, 2012

10.3K

帕雷科病毒:被忽视了太长时间?

Fahmida Alam1, You Li2, Matthew R Vogt1,2

  • 1Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Journal of virology
|March 25, 2025
PubMed
概括

帕雷科病毒感染了许多物种,在儿童中引起轻度疾病,但在婴儿中引起严重的神经疾病. 本综述检查了人类和非人类帕雷科病毒的特征,以了解它们的影响.

科学领域:

  • 病毒学 病毒学
  • 传染性疾病 传染性疾病
  • 分子生物学分子生物学

背景情况:

  • 帕雷科病毒是各种脊椎动物中发现的RNA病毒.
  • 人类感染很常见,引起轻微症状,但可能导致婴儿严重的神经疾病.
  • 动物帕雷科病毒与脑炎和围产期死亡等严重疾病有关.

研究的目的:

  • 审查人类和非人类帕雷科病毒的隔离史.
  • 分析全球分布,血清流行和进化方面.
  • 探索影响宿主特异性,毒性和致病性的因素.

主要方法:

  • 关于帕雷科病毒隔离和特征的文献综述.
  • 对全球分布和血清流行现有数据的分析.
  • 综合有关病毒生物学和进化的信息.

主要成果:

  • 帕雷科病毒在脊椎动物物种中具有广泛的宿主范围.
  • 临床表现和疾病严重程度存在显著差异.
  • 了解病毒生物学和进化对于解释宿主特定影响至关重要.

结论:

关键词:
这似乎是病毒.皮科纳病毒病毒.

更多相关视频

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
08:27

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat

Published on: October 29, 2014

13.1K
A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks
10:28

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

Published on: June 26, 2020

9.4K

相关实验视频

Last Updated: Apr 30, 2026

Efficient Recombinant Parvovirus Production with the Help of Adenovirus-derived Systems
13:47

Efficient Recombinant Parvovirus Production with the Help of Adenovirus-derived Systems

Published on: April 23, 2012

10.3K
Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
08:27

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat

Published on: October 29, 2014

13.1K
A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks
10:28

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

Published on: June 26, 2020

9.4K
  • 需要进一步的研究,以充分描述非人类帕雷科病毒.
  • 病毒进化和宿主免疫力等因素可能会影响疾病的动态.
  • 这一综述为未来关于帕雷科病毒病原和控制的研究提供了基础.