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血空气净化器对骨科手术中的感染率的影响

Anders Persson^1,2, Isam Atroshi^3,4, Thomas Tyszkiewicz⁵

¹Division of Orthopaedics, Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Sweden.

|March 25, 2025

概括

低成本的空气净化器没有减少骨科手术患者的手术部位感染 (SSI). 这项研究发现,使用活跃或非活跃空气净化器的手术室之间的感染率没有显著差异.

科学领域:

医学研究医学研究
传染病控制中的传染病控制
公共卫生公共卫生

背景情况:

手术部位感染 (SSI) 是骨科手术的一个重要问题.
空中传播是SSI的潜在原因.
标准的通风系统在降低SSI率方面有效性有限.

研究的目的:

研究低成本空气净化器在骨科手术后降低SSI率方面的有效性.
评估活性空气净化器对手术室感染标记物的影响.

主要方法:

一个全国性的,多中心,双盲,集群随机交叉,安慰剂控制的优越性试验.
包括所有接受骨科手术的患者.
在手术室使用主动空气净化器 (Novaerus NV800) 和非主动空气净化器 (Novaerus NV800) 的手术进行比较.
主要终点:12周内SSI,通过术后感染标志物 (PSIM) 定义.

主要成果:

分析了40,547名患者 (19,869名干预,20,678名对照).
干预组的PSIM率为9.2%,对照组为9.4% (OR为0.98,95% CI为0.91-1.05).
在各子组中没有观察到SSI率的显著差异.

结论:

挂在墙上的等离子体空气净化器没有降低骨科手术中的PSIM率.
在具有标准通风的现代手术室中,添加这些空气净化器是不有效的.

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