在存活了神经瘤下大脑关节出血的患者中,五年功能结果
Ho Seok Lee1, Min Kyun Sohn2, Jongmin Lee3
1Department of Physical and Rehabilitation Medicine, Center for Prevention and Rehabilitation, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
JAMA network open
|March 25, 2025
概括
动脉瘤下arachnoid出血 (aSAH) 患者的功能结果改善长达4年. 大多数患者取得了良好的结果,突出了持续管理和评估的必要性,以最大限度地提高恢复潜力.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 临床研究 临床研究
背景情况:
- 在动脉瘤下关节出血 (aSAH) 后功能恢复的纵向数据有限.
- 了解长期结果对于患者管理和康复策略至关重要.
研究的目的:
- 调查aSAH后患者的5年预后和功能结果.
- 分析功能恢复和死亡率的发展轨迹.
主要方法:
- 对338名aSAH患者的回顾性队列研究,来自韩国中风队列的功能和康复.
- 修改的兰金尺度 (mRS) 和功能独立度 (FIM) 的连续评估,从发病7天到5年.
- 统计分析包括威尔科克森签名等级测试,配对t测试和通用混合效应模型.
主要成果:
- 在7天的幸存者中,5年死亡率为8.3%.
- 修改的排名表得分在4年内显著改善,53.3%的得分为0和22.8%的得分为1.
- 功能独立性测量得分也显示了显著的改善,长达4年,然后平稳.
结论:
- 在aSAH患者的功能性结局持续改善至发病后4年.
- 大多数患者在最低限度的残疾的情况下经历了良好的结果.
- 强调长期评估和管理的重要性,以优化患者的康复.
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