相关实验视频

Updated: Aug 10, 2026

Formulating and Characterizing Lipid Nanoparticles for Gene Delivery using a Microfluidic Mixing Platform
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Formulating and Characterizing Lipid Nanoparticles for Gene Delivery using a Microfluidic Mixing Platform

Published on: February 25, 2021

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对脂质纳米粒子介导的mRNA输送进行PEGylated脂质查,组合优化和结构-活性关系的确定

Lingyun Liu1, Jae-Heon Kim1, Zhongyu Li1

  • 1mRNA Center of Excellence, Sanofi, Waltham, MA 02451, USA. Shri.Karve@Sanofi.com.

Nanoscale
|March 25, 2025
PubMed
概括

优化脂质纳米粒子 (LNP) 组成可以提高mRNA输送. 这项研究确定了关键的配方因素,包括PEGylated脂质和膜完整性,这对于有效的基于LNP的疫苗和疗法至关重要.

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