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Updated: May 7, 2026

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堕胎的个性化预测模型:深入的精子DNA碎片化

Chun-I Lee1,2,3, Tse-En Wang1, Chien-Hong Chen1,4

  • 1Division of Infertility Clinic, Taiwan, IVF Centers Lee Women'S Hospital, Taichung, Taiwan.

Journal of assisted reproduction and genetics
|March 25, 2025
PubMed
概括

精子DNA碎片化,特别是双链断裂 (DSB),在ICSI预后不佳的夫妇中显著影响流产风险. 对于这些患者,DSB测试可以完善治疗前评估.

关键词:
高级精液分析 精液分析损伤的DNA会导致DNA受损.流产 流产 流产父亲的影响.预测 预测 预测

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During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ovary, and travels into the fallopian tubes. The process requires several key steps: 1) sperm present in the genital tract must locate the egg; 2) once there, sperm need to release enzymes to help them burrow through the protective zona pellucida of the egg; and 3) the membranes of a single sperm cell and egg must fuse, with the sperm...