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Updated: May 20, 2025

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功能性cis元素的进化保守的星座编程了人类 (epi) 基因组对病毒反应的命运

Marianna A Koutsi1, Marialena Pouliou1, Dimitris Chatzopoulos1

  • 1Center of Basic Research, Biomedical Research Foundation, Academy of Athens, Athens 11527, Greece.

Nucleic acids research
|March 25, 2025
PubMed
概括

人类细胞使用新型病毒响应性cis-regulatory模块 (vrCRMs) 来控制免疫反应. 这些基因组元素,包括超级增强剂,对于抗病毒防御和维持平衡至关重要,影响自身免疫性疾病风险.

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