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中脑动脉动脉瘤和A1段变异的相关性

Xiaohui Li^1,2, Xi Yue², Zhengyuan Xie²

¹Department of Neurosurgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.

|March 25, 2025

概括

威利斯圆的变化,特别是A1段形,与中脑动脉动脉瘤有关. A1发育不良与较小的MCA直径和较大的动脉瘤大小有关,增加了破裂风险.

科学领域:

神经学神经学
血管外科血管外科
放射学放射学是一门学科.

背景情况:

来自威利斯圆变化的血液流动障碍有助于动脉瘤形成.
胎儿类型的后脑动脉 (PCA) 链接到后沟通动脉 (PcoA) 动脉瘤.
前脑动脉 (ACA) 变异与前沟通动脉 (ACoA) 动脉瘤相关.

研究的目的:

为了调查威利斯变异圆与中脑动脉 (MCA) 动脉瘤之间的有争议的关系.
在患有MCA动脉瘤和没有MCA动脉瘤的患者中分析威利斯圆的解剖变异.

主要方法:

对269例动脉瘤病例和269例对照患者的计算机断层扫描血管学 (CTA) 数据进行了回顾性分析.
使用3D-Slicer软件进行动脉直径测量和关系分析.
检查了威利斯变异和MCA动脉瘤相关性的循环.

主要成果:

在动脉瘤组中,A1细分发育不良明显更为普遍 (P = 0.0125).
动脉瘤患者的MCA直径较小 (2.304 ± 0.5613毫米) 与对照组 (2.611 ± 0.5500毫米,P = 0.001) 相比.
A1发育不良与较小的MCA直径,较大的动脉瘤大小以及发生/断裂风险增加相关.

结论:

威利斯圆的变化,特别是A1发育不良,影响MCA动脉瘤的发生和破裂.
改变的血流,收缩的母动脉直径,以及流量转移的影响都会导致MCA动脉瘤.
侧A1形是MCA动脉瘤发育和破裂的重要因素.

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