老年评估领域作为癌症老年人临床终点的预测指标:更新系统审查协议
Schroder Sattar1, Efthymios Papadopoulos2, Kristen R Haase3,4
1College of Nursing, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
PloS one
|March 25, 2025
概括
老年评估 (GA) 通过预测死亡率和治疗结果,帮助老年癌症患者. 识别关键的GA领域可以改善风险分层,当完全的评估是不可行的.
科学领域:
- 老年瘤学 老年瘤学
- 基于证据的医学 基于证据的医学
- 系统审查方法论 系统审查方法论
背景情况:
- 老年人评估 (GA) 对于指导癌症老年人的治疗决策和支持性护理至关重要.
- 识别预测结果的特定GA领域对于风险分层至关重要,特别是当全面评估不可行时.
研究的目的:
- 系统地审查和评估个别的老年医学评估领域作为癌症老年人的死亡率和治疗相关结果的预测指标.
- 为优化老年医学评估提供信息,以改善患者管理和结果.
主要方法:
- 从2017年7月起,对同行评审文献进行了更新的系统审查.
- 在Medline,Cochrane,Embase和CINAHL数据库中使用预定义的策略进行搜索.
- 独立选,至少两位作者进行数据提取,并对GA领域的切断值进行评估.
主要成果:
- 该审查将综合有关单个GA领域对死亡率和治疗结果的预测价值的证据.
- 分析将考虑异质性,GA工具/截止值的可变性,以及偏差风险.
- 如果满足异质性和数据可用性标准,将进行元分析.
结论:
- 个别的老年医学评估领域可以作为老年癌症患者死亡率和治疗结果的有价值的预测指标.
- 结果将指导精细化的老年病评估协议,以提高风险分层和个性化对这一群体的护理.
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