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Updated: May 20, 2025

A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
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作为刺激剂使用障碍的药物候选者,CM699的临床前资料

Takato Hiranita1, Weimin C Hong2, Abhisheak Sharma3,4,5

  • 1Department of Pharmacology, Joe R. and Teresa Lozano Long School of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas 78229, United States.

ACS chemical neuroscience
|March 25, 2025
PubMed
概括

一种新型化合物,CM699,通过双重多巴胺转运器和西格玛受体抑制,显示出治疗兴奋剂使用障碍的前景. 这种双重作用有效地阻止了在滥用潜力较低的临床前模型中自我管理可卡因.

关键词:
这是可卡因,可卡因.多巴胺运输体是多巴胺的运输体.自主管理的自治.西格玛1受体是什么?兴奋剂使用障碍

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