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对药剂师主导的干预措施进行系统审查和元分析,用于治疗胃潰瘍疾病
Biswash Sapkota1, Bipindra Pandey1, Bishal Sapkota2
1Department of Pharmacy and Clinical Pharmacology, Madan Bhandari Academy of Health Sciences, Hetauda, Nepal.
药剂师的干预显著改善了合理的抗药物使用. 这一系统性审查强调了它们对药物安全性,药物遵守性和患者护理成本效益的影响.
科学领域:
- 药理学 药理学是指药理学的学科.
- 临床药房 临床药房
- 基于证据的医学基于证据的医学.
背景情况:
- 药剂师在药物治疗规划,临床评估和药物监测方面发挥着至关重要的作用.
- 他们的干预对于预防药物错误和不良药物事件至关重要,提高整体药物安全.
- 在接受抗治疗的患者中,管理与药物相关的问题需要专门的药剂师投入.
研究的目的:
- 系统地审查和分析药剂师主导的干预措施,以管理在接受抗治疗的患者中与药物相关的问题.
- 评估这些干预措施对抗药物的合理使用的影响.
- 综合有关药剂师对该患者群体药物安全和药物遵守的贡献的证据.
主要方法:
- 从1904年到2024年6月发表的研究的系统审查和元分析.
- 在四个数据库中搜索相关文献.
- 包括9项研究 (四项追溯,三项病例对照,一项混合方法,一项前期后期研究) 与34,099名参与者. 使用修改后的纽卡斯尔-太华规模评估研究质量.
主要成果:
- 药剂师的干预显著改善了抗药物的合理使用 (OR:4.5;95%CI:0.97至20.80;P=0.05).
- 干预措施对药物坚持产生了积极影响,并纠正了不合理的药物使用.
- 高质量的研究 (平均得分6.22/7) 涉及直接的药剂师-患者或药剂师-医生互动.
结论:
- 药剂师主导的干预措施在改善合理使用抗药物方面是有效的.
- 这些干预措施有助于降低治疗成本和持续时间,并加强适当的药物使用.
- 药剂师是优化抗药物治疗和改善患者治疗结果的重要组成部分.
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