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优化用于引起声学变化复杂的刺激:评估正常听力成年人的过渡前刺激持续时间和刺激复杂性

Laura I A Schellekens¹, Marloes L Adank², Sarah Meehan²

¹Department of Otorhinolaryngology and Head and Neck Surgery, Erasmus Medical Center, Rotterdam, The Netherlands; Educational program Technical Medicine, Leiden University Medical Center, Delft University of Technology & Erasmus University Medical Center Rotterdam, The Netherlands.

Hearing research

|March 25, 2025

概括

在声变化复合体 (ACC) 测量中优化过渡前持续时间 (PTD) 可以提高信号对噪声的比率和效率. 建议使用1秒的PTD来提高听觉唤起潜能测试的临床可行性.

科学领域:

听觉神经科学听觉神经科学
神经生理学神经生理学
语音感知研究研究语音感知研究

背景情况:

声学变化综合体 (Acoustic Change Complex,简称ACC) 是一种皮质听觉唤起的潜能,对评估非可测试人群的言语歧视有价值.
目前ACC临床实用性的局限性源于长时间的测量时间,需要SNR优化.

研究的目的:

调查前过渡时间 (PTD) 和音调复杂度对ACC指标的影响.
评估对N1-P2振幅,噪声水平,信号噪声比 (SNR) 和测量效率的影响.

主要方法:

在18名听力正常的成年人中记录了ACC反应.
刺激包括带有频率变化和变化的PTD (0.25-3s) 的纯色调,以及带有1s PTD的复杂色调.

主要成果:

N1-P2振幅随着PTD增加到2s;PTD0.25s被排除在外.
将PTD从0.5s增加到1s显著提高了效率和SNR,将测量时间缩短了78.8%.
A 1s PTD最大限度地提高了效率和SNR;复杂的音调增加了ACC的存在,但不是SNR.

结论:

对于ACC测量,建议在0.5秒内进行1秒的PTD.
增加PTD超过1s和音调复杂度可以提高ACC的特异性,而不牺牲SNR或效率.
刺激优化对于提高ACC措施的临床适用性至关重要.

关键词:

声学变化复合体 (ACC) 是指声学变化复合体.皮层听觉唤起潜力 (CAEP)电脑电图 (EEG) 是一种电脑电图.频率变化变化频率变化正常的听力正常的听力过渡前的持续时间刺激的复杂性刺激的复杂性

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