睡眠呼吸障碍指数预测阻塞性睡眠呼吸暂停中发生的心房动:一项前性队列研究
Lixia Wang1, Xinjie Hui1, Wenhao Cao1
1Department of Pulmonary and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China.
Sleep medicine
|March 25, 2025
概括
阻塞性睡眠呼吸暂停 (OSA) 患者的睡眠呼吸障碍指数 (SBII) 分数较高,面临着心房动 (AF) 风险增加. 在预测OSA患者的AF方面,SBII比其他指标更有效.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 肺部病理学 肺部病理学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 与心血管并发症有关,特别是心房动 (AF).
- 在OSA期间间歇性缺氧是AF发展的独立风险因素.
- 需要新的指标来量化OSA的严重程度,并预测心血管事件.
研究的目的:
- 评估睡眠呼吸障碍指数 (SBII) 与OSA患者发生的AF之间的关联.
- 为了将SBII的预测性能与其他已建立的OSA AF风险严重性指数进行比较.
主要方法:
- 从睡眠心脏健康研究中对1660名OSA患者的分析,没有先前的AF.
- 将基线SBII值分为四分位数的分层,并在平均后续5.3年内评估事故AF.
- 多变量逻辑回归,受限立方线分析和C统计的比较 (SBII与HB,AHI,ODI).
主要成果:
- 在较高的SBII四分位数和发生性AF风险增加 (ORs1.87-2.01) 之间发现了显著的关联.
- 缺氧负担 (HB) 也显示出与增加AF风险的关联 (第四四分位数的OR为1.70).
- 与HB,AHI和ODI相比,SBII表现出事件AF的优异预测性能,具有最高的C统计值 (0.75).
结论:
- 升高的SBII和HB水平与患有OSA的患者患有AF的风险更高.
- 在OSA患者中,SBII比其他常用的严重性指数更有效地预测发生的AF.
相关概念视频
Sleep Apnea
120
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
120
Physical Assessment of the Respiratory Tract II: Inspection
207
Physical assessment of the respiratory tract through inspection is a crucial step in understanding the patient's respiratory health. It provides insights into the functioning of the respiratory system, the musculoskeletal structure, and even the patient's nutritional status. This comprehensive approach involves observing several vital aspects: chest configuration, breathing patterns, respiratory rates, skin color, and use of accessory muscles.
Chest Configuration
The chest configuration...
Chest Configuration
The chest configuration...
207
Acute Respiratory Failure-IV
115
Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
115
Respiratory Volumes and Capacities I
791
Assessing the respiratory rate and rhythm for a complete minute is crucial for evaluating the breathing pattern. Even a minor increase in the patient's average respiratory rate, by as little as three to five breaths per minute, is an early and vital indicator of respiratory distress. Patients with a respiratory rate exceeding twenty-four breaths per minute require close monitoring to determine the physiological alterations. This careful observation is essential for prompt recognition and...
791
Assessment of Ventilation II: Respiratory Depth and Rhythm
1.3K
Respiratory Depth
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
1.3K
Assessment of Airway, Skin Color, and Use of Accessory Muscles
945
A thorough assessment of respiratory health is paramount in clinical settings to identify and manage respiratory distress and ensure adequate oxygenation. This article elaborates on the critical aspects of respiratory evaluation, including airway assessment, skin color examination, and the observation of accessory muscle use, which are integral to effectively diagnosing and managing patients with respiratory conditions.
Introduction
The initial evaluation of a patient's respiratory system...
Introduction
The initial evaluation of a patient's respiratory system...
945


