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Updated: May 20, 2025

Ubiquitin Chain Analysis by Parallel Reaction Monitoring
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UbiREAD破译了同型和分支的K48和K63泛素链的蛋白质体降解代码

Leo Kiss1, Leo C James2, Brenda A Schulman1

  • 1Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried 82152, Germany.

Molecular cell
|March 25, 2025
PubMed
概括

研究人员开发了一种新的技术,UbiREAD,以比较不同泛素链如何影响蛋白质降解. 这项研究揭示了泛素链的特定代码,根据链接,长度和结构来决定蛋白质命运.

关键词:
K48 K48 K48 K48 K48 K48 K48 K48 K48 K48 K48 K48 K48K63 K63 K63 K63 K63 K63 K63 K63 K63 K63 K63 K63 K63 K63 K63 K63 K63 K63 K63 K63 K63 K63分支的无处不在的链.必须进行脱离分离.电穿孔的电穿孔是一种蛋白质酶体蛋白质组是什么蛋白质降解 蛋白质降解蛋白质稳定症是一种蛋白质稳定症.在任何地方都是无处不在的.无处不在的代码

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