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Updated: May 20, 2025

Primary Cultures of Rat Astrocytes and Microglia and Their Use in the Study of Amyotrophic Lateral Sclerosis
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Published on: June 23, 2022

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单细胞转录组和功能研究确定了质状态的变化以及炎症RIPK1信号在ALS病变发生过程中的作用

Matija Zelic1, Anna Blazier1, Fabrizio Pontarelli1

  • 1Sanofi, Rare and Neurologic Diseases, Cambridge, MA 02141, USA.

Immunity
|March 25, 2025
PubMed
概括

肌缩侧面硬化症 (ALS) 中的神经炎症涉及改变的质细胞和RIPK1通路. 在小鼠模型中阻断RIPK1延迟了疾病进展和运动缺陷.

关键词:
这就是ALS.在RIPK1中使用.星球细胞是星球细胞.微质细胞中的微质细胞神经炎症是一种神经炎症.一个核的RNA-seqq.

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