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Updated: May 20, 2025

Tracking Bispecific Antibody-Induced T Cell Trafficking Using Luciferase-Transduced Human T Cells
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在瘤微环境中选择性激活互白素-2/互白素-15受体信号,使用对联双特异性抗体

Julien Montorfani1,2, Eric Hatterer1, Laurence Chatel1

  • 1Light Chain Bioscience - Novimmune S.A, Plan-Les-Ouates, Geneva, Switzerland.

Journal for immunotherapy of cancer
|March 25, 2025
PubMed
概括

这项研究开发了双特异性抗体 (bsAbs),以向癌症免疫疗法中的介质素-2 (IL-2) 和介质素-15 (IL-15). 新的bsAbs选择性地激活瘤内的免疫细胞,减少全身毒性并增强抗瘤作用.

关键词:
抗体是对抗体的一种.细胞因子细胞因子免疫治疗是一种免疫疗法.一个T细胞细胞.瘤微环境 - - 瘤微环境

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