全免疫-炎症值:在接受非 CABG 的年轻患者中预测术后心房动的新型生物标志物
Mustafa Selcuk Atasoy1, Hakan Guven2
1Department of Cardiovascular Surgery, Bursa City Hospital, Bursa, Turkey.
Journal of cardiothoracic and vascular anesthesia
|March 25, 2025
概括
全免疫-炎症值 (PIV) 和中性粒细胞与淋巴细胞比率 (NLR) 可以预测在年轻患者的冠状动脉旁路移植 (CABG) 后新发动心房动 (AF). 307.9的PIV是预测CABG后AF的最佳切线.
科学领域:
- 心血管外科心血管外科
- 心脏病学 心脏病学
- 炎症研究 炎症研究
背景情况:
- 新发性心房动 (AF) 是冠状动脉旁路移植 (CABG) 后的常见并发症.
- 术后AF的预测标志物,特别是在非 CABG (OPCABG) 的背景下,需要进一步调查.
- 全免疫炎症值 (PIV) 是一种反映系统性炎症的新标志物.
研究的目的:
- 在接受OPCABG的年轻患者中研究PIV对新发性AF的预测价值.
- 为了确定PIV是否是术后AF的独立预测因子,在OPCABG之后.
主要方法:
- 对223名接受OPCABG的年轻患者 (年龄≤50岁) 进行了回顾性观察队列研究.
- 患者被分为AF (n=31) 和非AF (n=192) 组.
- 使用后勤回归和ROC曲线分析来确定预测因素和最佳切割值.
主要成果:
- 在AF和非AF组之间,PIV和中性粒细胞与淋巴细胞比率 (NLR) 显著不同.
- PIV (OR 1.001,95% CI 1.000-1.002) 和NLR被确定为术后AF的独立预测因素.
- 预测AF的最佳PIV切线为307.9,具有93.5%的灵敏度和71.4%的特异性.
结论:
- 在年轻患者中,PIV是OPCABG后新发性AF的显著和独立预测因素.
- 此外,NLR还独立预测了OPCABG后新出现的AF.
- 在接受OPCABG的患者中,PIV为AF风险分层提供了有价值的工具.
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