在患有多种长期疾病的患者出院后,药物清单中的差异
Malin Olsen Syversen1, Mikas Glatkauskas1, Sandra Johanne Sedeniussen1
1Department of Pharmacy, Section for Pharmacology and Pharmaceutical Biosciences, University of Oslo, Oslo, Norway.
Research in social & administrative pharmacy : RSAP
|March 25, 2025
概括
在患有多种长期疾病的患者出院后,药物不一致是常见的. 随着时间的推移,未被纠正的差异对患者安全构成越来越大的风险.
科学领域:
- 药监和患者安全 药监和患者安全
- 医疗保健服务研究 医疗服务研究
- 老年医学 老年医学
背景情况:
- 在从医院到家庭的过渡过程中,信息流量不足会影响药物安全,特别是在患有多种长期疾病 (MLTC) 的患者中.
- 有效的药物管理对于这个脆弱的患者群体来说至关重要,以防止不良事件.
研究的目的:
- 在医院出院时量化MLTC患者的药物差异 (MDs).
- 为了分类MD,确定潜在的原因,并评估它们的短期和长期临床相关性.
- 为了比较医院出院总结与实际出院后的药物使用情况.
主要方法:
- 150名在家住宿的成年患者的横截面观察性研究,其中至少有四种药物的MLTC.
- 药物调和在出院后1-2周进行,比较出院总结与患者药物使用情况.
- 医学博士分为六类;临床相关性由专家小组评估.
主要成果:
- 88%的患者 (n=150) 经历了至少一个MD,每位患者的中位数为3.
- 大多数常见的MD涉及使用的药物,但未在出院摘要中列出.
- 住院期间药物调和不足是MDs的主要原因.
结论:
- 几乎所有患有MLTC的患者在出院后都会出现药物差异.
- 未解决的MD的潜在临床相关性随着时间的推移显著增加.
- 加强干预措施对于改善这种人群在护理过渡期间的药物安全至关重要.
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