药剂师干预对提高疫苗接种范围的影响:系统性审查和元分析
Yomna Elghanam1, Eun Young Kim2
1Data Science, Evidence-Based and Clinical Research Laboratory, Department of Health, Social, and Clinical Pharmacy, College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea.
Research in social & administrative pharmacy : RSAP
|March 25, 2025
概括
药剂师的干预显著提高了疫苗接种率,特别是当药剂师直接接种疫苗时. 扩大这些服务可以提高全球免疫覆盖率,并打击疫苗犹.
科学领域:
- 公共卫生 公共卫生
- 药房实践 在药房实践.
- 疫苗学 疫苗学 疫苗学
背景情况:
- 尽管有疫苗可用,但疫苗接种率仍然低于最佳水平.
- 药剂师是可访问的医疗保健提供者,有可能改善免疫.
- 干预措施包括教育,宣传和药剂师直接免疫.
研究的目的:
- 系统地审查和元分析药剂师干预对疫苗接种率的影响.
- 评估药剂师在改善免疫覆盖率方面的有效性.
主要方法:
- 在PubMed,Embase和Web of Science中对RCT和集群RCT进行系统搜索,直到2024年11月.
- 主要结果:疫苗接种率. 使用Cochrane工具评估偏差风险2.使用Cochrane工具进行评估.
- 使用随机效应模型进行的元分析;在PROSPERO.中注册的评论.
主要成果:
- 在分析中包括的17个RCT显示,药剂师干预显著增加了疫苗接种率 (RR 1.58,P < 0.00001).
- 观察到很高的异质性 (I2 = 93%).
- 作为免疫剂的药剂师 (RR 1.76) 的影响比作为倡导者的影响更大 (RR 1.59).
结论:
- 药剂师的参与显著提高了疫苗接种率,特别是当他们作为免疫剂时.
- 扩大药剂师在疫苗接种服务中的角色,特别是在发展中国家,可以提高全球覆盖率.
- 这些发现支持药剂师解决疫苗犹和改善公共卫生结果.
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