多细胞血症的神经眼科表现
Grace Y Zhou1, Sarah Aman, Saif Aldeen Alryalat
1Baylor College of Medicine (GYZ), Houston, Texas; The Wilmer Eye Institute (SA), The Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Ophthalmology (SAA, OAD, AGL), Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas; Department of Ophthalmology (SAA), The University of Jordan, Amman, Jordan; Department of Ophthalmology (SH), Copenhagen University Hospital-Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine (SH), University of Copenhagen, Copenhagen, Denmark; Department of Ophthalmology (AGL), Cullen Eye Institute, Baylor College of Medicine, Houston, Texas; Departments of Ophthalmology, Neurology, and Neurosurgery (AGL), Weill Cornell Medicine, New York, New York; Department of Ophthalmology (AGL), University of Texas MD Anderson Cancer Center, Houston, Texas; Texas A&M College of Medicine (AGL), Bryan, Texas; and Department of Ophthalmology (AGL), The University of Iowa Hospitals and Clinics, Iowa City, Iowa.
多细胞血症可能会导致严重的视力问题由于高粘度,导致事件,如暂时失明. 早期发现和治疗多细胞血症对于预防不可逆转的视力丧失至关重要.
科学领域:
- 神经眼科 神经眼科
- 血液学 血液学 血液学
- 血管医学 血管医学
背景情况:
- 与多细胞血症相关的高粘度可能会导致眼血管事件.
- 这些事件的范围从暂时的视力丧失到如果不治疗,就会造成永久的视力损伤.
研究的目的:
- 在患有多细胞血症的患者中调查神经眼科症状.
- 审查类似病例的文献,并讨论诊断和治疗策略.
主要方法:
- 一个多中心, 4 个患者的回顾性病例系列.
- 使用PubMed数据库对类似案件的文献综述.
主要成果:
- 四名患者呈现出各种症状,包括视力丧失和视觉神经病变.
- 多细胞血症在3例中是治疗的次要原因,在1例中是主要原因 (真多细胞血症).
- 其他14例从文献中显示出类似的视力损失症状.
结论:
- 多细胞血是导致眼血管事件的一个重要因素.
- 对这些患者来说,仔细的临床评估和管理是必不可少的.
- 需要进一步的研究来了解血液动力学变化,并优化眼部健康治疗.
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