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Updated: May 22, 2025

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
00:06

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

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在FRS3中Missense变异会影响不同祖先的种群体质量指数

Andrea B Jonsdottir1,2, Gardar Sveinbjornsson3, Rosa B Thorolfsdottir3

  • 1deCODE genetics/Amgen Inc., Reykjavik, Iceland. andrea.jonsdottir@decode.is.

Nature communications
|March 26, 2025
PubMed
概括

大规模的基因分析发现了MC4R附近的显著删除增加了BMI和一个罕见的FRS3变异降低了BMI. 这项研究促进了对肥胖的理解.

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