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Updated: May 20, 2025

In Vitro Assay for Studying the Aggregation of Tau Protein and Drug Screening
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基于蛋白位点和图案的几何预测与错误折叠和聚合相关

Masumi Sugiyama1,2, Kenneth S Kosik3, Eleni Panagiotou4

  • 1Department of Mathematics, University of Tennessee at Chattanooga, Chattanooga, TN, 37403, USA.

Scientific reports
|March 26, 2025
PubMed
概括

应用于tau蛋白的数学拓和几何学揭示了特定的聚合易感位点,如PGGG和PHF6(*). 不同的多病症表现出不同的结构层次和能量景观,将本地和全球的拓特征与疾病进展相关联.

关键词:
聚合是一种聚合.几何几何学的几何学神经退行性疾病是一种神经退行性疾病.结构 结构 是一个结构.陶氏蛋白质是一种陶氏蛋白质.拓学的拓学

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