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在单细胞衍生巨细胞中对SARS-CoV-2mRNA疫苗接种的持续表观遗传记忆

Alexander Simonis1,2,3, Sebastian J Theobald1,2,3, Anna E Koch2

  • 1Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, 50937, Germany.

Molecular systems biology
|March 26, 2025
PubMed
概括

mRNA疫苗通过表观遗传记忆来训练先天性免疫细胞,特别是基因组 H3 lysine 27 乙化 (H3K27ac). 这种训练增强了免疫反应,并通过增强剂注射来维持.

关键词:
表观遗传记忆 是一种表观遗传记忆.在G-quadruplex中使用.H3K27ac 在线阅读在SARS-Cov-2 mRNA疫苗接种过程中训练有素的天生的免疫力

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