没有腹腔疾病的成年人避免质的患病率和特征:长期基于人口的随访研究
Miska Tiainen1, Kalle Kurppa1,2,3, Tuija Jääskeläinen4
1Celiac Disease Research Center, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, Elämänaukio 2, Tampere, Finland.
BMC gastroenterology
|March 26, 2025
概括
在过去的十年中,在芬兰,避免食用无乳的人数 (PWAG) 显著增加. 这个群体还报告了更多的特殊饮食和心理社会负担的迹象.
科学领域:
- 流行病学 流行病学
- 胃肠病学 胃肠病学
- 公共卫生 公共卫生
背景情况:
- 对于那些避免使用质而没有患有乳病 (PWAG) 的人,全国范围的患病率和长期随访数据有限.
- 了解PWAG的趋势和特征对于公共卫生倡议至关重要.
研究的目的:
- 评估2000年至2011年间芬兰人口基队列中PWAG的流行,发病率和特征.
- 在没有被诊断出患有乳病的情况下,确定避免质的潜在预测因素.
主要方法:
- 利用了2000年和2011年芬兰健康调查的数据,分别包括5,777名和3,866名成年人.
- 分析了参与两项调查的3296名个人.
- 使用一般健康问卷和贝克抑郁症清单评估心理健康;测量乳病查的自身抗体.
主要成果:
- PWAG的患病率从2000年的0.2%大幅上升至2011年的0.7% (p < 0.001).
- 在2011年,PWAG组更有可能遵循额外的限制性饮食,如无乳糖 (41.7%对12.0%) 和与过敏有关的限制 (12.5%对3.0%).
- 2000年,PWAG的抑郁症得分较高 (p = 0.023),但2011年在心理评估中没有发现显著差异.
- 鉴定了乳病的风险因素 (例如,女性性别,贫血症) 并不能预测以后避免质.
结论:
- 芬兰PWAG的患病率在十年内增加了三倍以上,到2011年达到0.7%.
- PWAG经常坚持多种饮食限制,可能会经历心理社会负担.
- 在这个队列中,没有发现特定的预测因素来发展避免质的习惯,而没有患有乳病.
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