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相关概念视频

Sex-linked Disorders01:43

Sex-linked Disorders

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Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
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Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
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Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
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Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
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The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
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Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
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相关实验视频

Updated: May 20, 2025

Laparoscopic Oocyte Retrieval and Cryopreservation during Vaginoplasty for Treatment of Mayer-Rokitansky-Kuster-Hauser Syndrome
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[沃格特-科亚纳吉-哈拉达综合征]

Dana Cohen1, Yael Ben-Arie-Weintrob2, Tamar Hareuveni-Blum3

  • 1Department of Ophthalmology, Galilee Medical Center, Nahariya.

Harefuah
|March 26, 2025
PubMed
概括

作为一种自身免疫性疾病的Vogt-Koyanagi-Harada (VKH) 综合征可以导致严重的视力丧失. 早期诊断和使用类固醇,免疫抑制剂和生物药物的治疗对于管理VKH并发症至关重要.

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科学领域:

  • 眼科医生 眼科 眼科
  • 类风湿病学 类风湿病学
  • 免疫学 免疫学 免疫学

背景情况:

  • 沃格特-科亚纳吉-哈拉达综合征 (VKH) 是一种罕见的自身免疫性疾病,引起全眼炎症.
  • 它可以导致系统性症状,如听力损失和神经系统问题.
  • 慢性炎症和发作可能会导致显著的视力丧失.

研究的目的:

  • 介绍一个病例报告和文献综述的Vogt-Koyanagi-Harada综合征.
  • 讨论眼部和全身表现,诊断和治疗.
  • 突出早期干预在VKH的重要性.

主要方法:

  • 一个14岁的患者的病例报告,患有双边颗粒状膜炎.
  • 对传染病和类风湿病进行全面的检查.
  • 关于VKH表现,诊断和治疗的文献评论.

主要成果:

  • 患者最初出现了视膜炎和视神经/视网膜.
  • 最初的类固醇治疗不足,随后的成像证实了VKH.
  • 用免疫抑制剂 (Imuran,Cyclosporin) 和生物药物治疗显示出良好的反应.

结论:

  • 早期诊断和及时,适当的治疗对于VKH管理至关重要.
  • 包括免疫抑制剂和生物药物在内的多方面的治疗可以有效控制VKH.
  • 尽量减少眼部和眼外并发症需要及时和积极的治疗策略.