对脊髓刺激用于幻肢疼痛的范围审查
Stephen Jaffee1, Rhea Verma2, Mariam Vaezi1
1Department of Neurosurgery, Allegheny Health Network Neuroscience Institute, Pittsburgh, PA, USA.
Interventional pain medicine
|March 26, 2025
概括
脊髓刺激 (SCS) 为幻肢疼痛 (PLP) 患者提供疼痛减轻,有些人获得了显著的缓解. 然而,存在诸如伤口感染等并发症,需要进一步研究长期疗效.
科学领域:
- 神经学 神经学
- 疼痛管理 疼痛管理
- 神经外科 神经外科
背景情况:
- 幻肢疼痛 (PLP) 是截肢后的一个具有挑战性的疾病.
- 标准治疗包括抗药和物理治疗.
- 脊髓刺激 (SCS) 是耐火性PLP的一个选择.
研究的目的:
- 系统地审查用于PLP的SCS文献.
- 评估PLP患者中与SCS相关的疼痛减轻和并发症率.
主要方法:
- 对用SCS治疗的PLP成年人研究的系统审查.
- 标题/摘要的选,然后进行全文审查.
- 关于疼痛分数 (VAS,BPI),位和并发症的数据提取;描述性分析.
主要成果:
- 五份报告包括33名患者;观察到不同程度的疼痛减轻 (高达100%).
- 报告了显著的疼痛减轻,平均VAS减轻50%和中位数BPI减轻43.5%.
- 并发症包括伤口感染 (6%),短暂的软弱 (3%) 和其他;84.8%的患者患有外围导管.
结论:
- 在一些PLP患者中,SCS可以有效地减轻疼痛,其中一部分患者经历了相当大的缓解.
- 并发症,特别是伤口感染,是令人担忧的.
- 需要进一步的研究来确认长期疗效,并优化SCS用于PLP治疗.
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