利用质谱学了解Angelicae sinensis的根部中的营养物质和金属元素分布
Shiyu He1, Boyan Li1, Lan Wang2
1School of Public Health/Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, Guizhou Medical University, Guiyang 561113, China. Boyan_Li@hotmail.com.
Analytical methods : advancing methods and applications
|March 26, 2025
概括
这项研究分析了401批干燥的Angelica sinensis根 (RAS),详细说明了营养和金属元素的分布. 结果提供了关于RAS质量控制和健康益处的见解.
科学领域:
- 药物鉴定学是指药物鉴定学.
- 营养科学 营养科学
- 分析化学 分析化学
背景情况:
- 天 (Angelica sinensis) 是一种具有药用和食品用途的植物.
- 它的干燥根 (Angelicae sinensis根,RAS) 含有有价值的营养素和生物活性化合物.
- 了解RAS的组成对于质量控制和健康应用至关重要.
研究的目的:
- 在401个RAS批次中对24种营养素和15种金属元素的分布进行定量分析.
- 引入一种用于多变量分析的新型综合生物可访问性响应方法.
- 提供有关RAS质量,健康益处和应用的见解.
主要方法:
- 超高性能液体染色学-并联质谱学 (UHPLC-MS/MS) 用于营养分析.
- 感应合等离子体质谱 (ICP-MS) 和原子吸收光谱 (AAS) 用于金属元素分析.
- 开发和应用一种新的综合生物可访问性响应方法.
主要成果:
- 在各种RAS批次中确定了24种营养素和15种金属元素的详细定量分布.
- 该研究成功地应用了一种新的多变量统计方法来分析多组件反应.
- 根据地理来源和收获时间观察到营养和金属元素配置的变化.
结论:
- 这项研究提供了RAS的全面组成概况,有助于其质量标准化.
- 这些发现提高了对RAS潜在健康益处的理解,并支持其广泛使用.
- 新的生物可访问性响应方法为分析复杂的天然产品成分提供了一个新的工具.
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