运动强度,持续时间和体积对人类耐力运动期间蛋白质氧化的影响:通过元分析进行系统性审查
Matthieu Clauss1, Jørgen Jensen1
1Department of Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway.
Scandinavian journal of medicine & science in sports
|March 26, 2025
概括
耐力运动显著增加蛋白质氧化,与休息相比,它翻了一番以上. 这种增加主要是由运动强度驱动的,而不是持续时间或体积.
科学领域:
- 运动生理学 运动生理学
- 营养生物化学 营养生物化学
- 运动科学 运动科学 运动科学
背景情况:
- 在耐力运动期间,蛋白质代谢和氨基酸利用率有所不同.
- 缺乏对运动期间蛋白质氧化率的明确理解.
- 现有的研究对蛋白质在运动能量消耗中的作用提出了分散的看法.
研究的目的:
- 通过汇总现有数据,估计耐力运动期间的蛋白质氧化率.
- 分析运动强度,持续时间和体积对蛋白质氧化的影响.
- 为了建立一个更明确的共识蛋白质代谢在长时间的体力活动.
主要方法:
- 在PubMed和谷歌学者的系统文献搜索 (2023年3月) 进行英语语言研究.
- 纳入标准:蛋白质代谢测量 (排泄,白氧化或氨基酸利用指标),耐力运动与对照,详细的运动方案和健康的成年参与者.
- 对30项研究 (n=286) 的分析,涉及至少60分钟的跑步,骑自行车或越野滑雪.
主要成果:
- 在耐力运动中,蛋白质氧化增加了1.02 mg·kg−1·min−1,而在休息时则增加了0.81 mg·kg−1·min−1.
- 蛋白质对运动期间的总能耗贡献了3.28%.
- 蛋白质氧化率通过运动持续时间正常化,随着运动强度的提高而显著增加;持续时间和体积没有显著影响.
结论:
- 本综述提供了第一个关于耐力运动期间蛋白质氧化的综合数据,涉及各种测量方法.
- 耐力运动始终提高蛋白质氧化,比休息水平增加一倍多.
- 运动强度是耐力运动期间蛋白质氧化率的关键决定因素.
相关概念视频
01:27Exercise and Muscle Performance
1.3K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
1.3K
01:20Exercise and Cardiovascular Response
683
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
683
01:17Exercise and Cardiac Output
793
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
793
01:24Muscle Recovery and Fatigue
1.9K
Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective...
1.9K
01:15Pyruvate Oxidation
157.8K
After glycolysis, the charged pyruvate molecules enter the mitochondria via active transport and undergo three enzymatic reactions. These reactions ensure that pyruvate can enter the next metabolic pathway so that energy stored in the pyruvate molecules can be harnessed by the cells.
First, the enzyme pyruvate dehydrogenase removes the carboxyl group from pyruvate and releases it as carbon dioxide. The stripped molecule is then oxidized and releases electrons, which are then picked up by NAD+...
First, the enzyme pyruvate dehydrogenase removes the carboxyl group from pyruvate and releases it as carbon dioxide. The stripped molecule is then oxidized and releases electrons, which are then picked up by NAD+...
157.8K