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对于全乳腺强度调节的辐射疗法的体内过渡剂量计方法

Lucia Zirone¹, Elisa Bonanno¹, Giuseppina R Borzì¹

¹Medical Physics Department, Humanitas Istituto Clinico Catanese, Misterbianco, Italy.

Journal of applied clinical medical physics

|March 26, 2025

概括

在全乳腺IMRT中,一种新的体内过渡剂量测量方法 (EPID-IVTD) 提高了放射治疗的准确性. 这种标准化的方法通过在临床实践中实现有效的治疗监测,提高了患者的安全性.

科学领域:

医学物理医学物理
辐射瘤学辐射瘤学
放射治疗技术放射治疗技术

背景情况:

使用电子门户成像设备 (EPID-IVTD) 的体内传输剂量测量对于验证放射治疗的准确性至关重要.
乳腺强度调节放射治疗 (IMRT) 的EPID-IVTD缺乏标准化,这阻碍了临床采用.
一种标准化的EPID-IVTD方法可以提高治疗准确性和患者安全性.

研究的目的:

为EPID-IVTD开发一种标准化的方法,专门用于全乳腺IMRT治疗.
为乳腺癌患者在临床实践中实施EPID-IVTD建立可靠的协议.

主要方法:

在50名患者的数据集上利用了马传递率 (GPRs) 分析.
根据剂量测量协议,确定第一个治疗分数作为参考分数.
实施了EPID-IVTD监测,使用AAPM TG 218较低容忍度 (l-TL) 和行动极限 (l-AL) 作为警报和报警值.

主要成果:

由于最佳的剂量测量协议,初始治疗分数作为参考.
在EPID-IVTD监测中,75%的病例中显示了97.5%至99.9%的GPR.
分析显示,93.83%的GPR高于l-TL,4.31%在l-TL和l-AL之间,1.86%低于l-AL.

结论:

一个实用和有效的EPID-IVTD全乳腺IMRT方法已经成功开发出来.
这种方法现在已经被整合到中心的常规临床实践中,以有效监测治疗.
开发的EPID-IVTD方法提高了乳腺IMRT治疗的质量保证.

关键词:

在EPID中,我们可以使用EPID.玛传递率的通过率在活体中过境剂量计.

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