维生素D注射对状体和高变性痕的影响
Amel R Hassan1, Ammena Y Binsaleh2, Samar M El-Tahlawi1
1Department of Dermatology, STDs and Andrology, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Journal of cosmetic dermatology
|March 26, 2025
概括
维生素D注射改善了痕血管性和曲性,在患有过度缩痕和 keloids 的患者. 维生素D缺乏没有影响痕严重程度,但治疗改善了所有患者的治疗结果.
科学领域:
- 皮肤病学 皮肤病学
- 内分泌学 在内分泌学.
- 伤口愈合 治愈 伤口愈合
背景情况:
- 过度缩性痕和状体是由皮肤损伤引起的纤维扩散性疾病.
- 维生素D在抑制 keloid 纤维细胞增殖和调节细胞外矩阵形成方面发挥作用.
研究的目的:
- 为了研究内部和全身维生素D3注射在治疗过度缩痕和 keloids 的疗效.
- 为了确定维生素D缺乏是否会影响痕的发展和严重程度.
主要方法:
- 30名患有缩性痕/形状的患者被按血清维生素D水平分组.
- 第一组接受了系统和内伤维生素D3与;第二组接受了内伤维生素D3.
- 使用ELISA评估血清维生素D水平;使用温哥华痕量表评估痕严重程度.
主要成果:
- 维生素D缺乏与痕形成或严重程度无关.
- 所有患者都在痕血管性,可性和温哥华痕量表总体得分方面显著改善.
- 没有观察到痕颜色或身高的显著变化,并且在治疗后的组之间没有发现显著差异.
结论:
- 维生素D注射增强了足够和缺乏维生素D的患者的痕血管性和柔性.
- 系统性维生素D补充剂在内伤治疗之前改善了缺乏维生素D的患者的水平.
- 治疗没有影响痕高度或颜色.
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