早期检测和结肠直肠癌查的年龄比较分析:土耳其人口的见解
Cem Batuhan Ofluoğlu1, Fırat Mülküt2, İsa Caner Aydın3
1Department of Gastroenterology Surgery, Sancaktepe Training and Research Hospital, University of Health Sciences, 34785 Istanbul, Turkey .
Current oncology (Toronto, Ont.)
|March 26, 2025
概括
在土耳其45-49岁无症状患者的结肠直肠癌 (CRC) 查显示了较低的聚体检测,但强调了由于早期发病的晚期结肠直肠瘤 (EAO-CRN) 患病率高,因此需要进行早期查.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 结肠直肠癌 (CRC) 查指南各不相同,最近一些人群转向更早的年龄.
- 在更年轻的无症状成年人中评估结肠镜的诊断产量对于完善查策略至关重要.
- 了解CRC患病率和风险因素的区域差异对于有针对性的预防至关重要.
研究的目的:
- 将45-49岁无症状个体的查结肠镜的诊断产量与土耳其50-54岁的无症状个体的诊断产量进行比较.
- 评估这些年龄组中多和早期发病的晚期结直肠瘤 (EAO-CRN) 的患病率.
- 为特定区域的CRC查策略提供信息.
主要方法:
- 在土耳其的三个第三级内镜单位 (2018-2023) 中,对3943名45-54岁无症状个体的查结肠镜数据进行了回顾性分析.
- 患者被分为两组:45-49岁 (第一组) 和50-54岁 (第二组).
- 分析的数据包括人口特征,多检测率,腺瘤检测率,高级多检测率和EAO-CRN流行率.
主要成果:
- 在第一组 (16.6%) 与第二组 (22.9%) (p < 0.001) 相比,整体的聚检测率明显较低.
- 在第一组中,先进的息肉检测率为3.2%,而在第二组为7.3% (p < 0.001).
- 尽管检测率较低,但EAO-CRN在45-49岁年龄组的流行率强调了这一发现的意义.
结论:
- 与50-54岁的人相比,在土耳其对45-49岁无症状个体的查产生了较少的息肉和晚期瘤.
- 年轻人群体中EAO-CRN的存在强调了考虑早期查的重要性,特别是在高风险人群中.
- 优化CRC预防政策需要量身定制的区域战略,包括个别风险因素.
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