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一个基于智能手机的便携式3D打印生物传感平台,用于功能生物标志物量化.

Sangeeta Palekar1, Sharayu Kalambe2, Jayu Kalambe1

  • 1Department of Electronics Engineering, Ramdeobaba University, Nagpur 440013, MH, India.

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概括

一个新的3D打印传感器平台,可以便携式检测功能生物标志物,如尿酸,肌素和白蛋白. 这种具有成本效益的设备提供了准确的实时血液分析,用于点诊断诊断.

关键词:
通过3D打印打印3D打印.颜色测量仪的颜色测量方法诊断 诊断 诊断 诊断 诊断卫生监测健康监测脏生物标志物的生物标志物照顾点的检测测试智能手机的智能手机智能手机的智能手机.

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科学领域:

  • 生物医学工程 生物医学工程
  • 分析化学 分析化学
  • 临床诊断 临床诊断 临床诊断 临床诊断

背景情况:

  • 早期发现病对于有效的管理和治疗至关重要.
  • 目前的诊断方法可能很复杂,需要专门的实验室设备.
  • 需要易于使用,便携和具有成本效益的工具来监测功能.

研究的目的:

  • 开发一个便携式,3D打印的色度传感器平台,用于检测关键的功能生物标志物.
  • 为了能够准确和实时分析血清中的尿酸,肌素和白蛋白.
  • 创建一个用户友好的系统,用于点的护理诊断和远程健康监测.

主要方法:

  • 设计了一个3D打印平台,集成LED照明和一次性流量电池.
  • 用智能手机成像分析了血清生物标记物与试剂的色度反应.
  • 为数据处理和分析开发了一个自适应校准算法和一个Android应用程序.
  • 度是使用RGB值和贝尔-兰伯特定律计算的.

主要成果:

  • 传感器平台展示了良好的尿酸,肌素和专素的线性检测范围.
  • 实现了低检测极限:尿酸为1.15 mg/dL,肌素为0.15 mg/dL,白蛋白为0.11 g/dL.
  • 结果显示与商业生物化学分析仪有很强的相关性.
  • 该系统在不同的智能手机,试剂和照明条件中表现出灵活性和准确性.

结论:

  • 开发的3D打印传感器平台是用于检测功能生物标志物的便携式,具有成本效益的解决方案.
  • 该系统提供准确的,实时的血液分析,适合于点的护理设置.
  • 这项技术在改善病诊断和远程患者监测方面具有重大潜力.