关于睡眠时间和血压之间的关系的调查结果和方法上的缺陷:全面的叙述审查
Michael H Smolensky1,2, Ramón C Hermida1,3,4, Richard J Castriotta5
1Department of Biomedical Engineering, Cockell School of Engineering, The University of Texas at Austin, Austin, TX 78712, USA.
Journal of cardiovascular development and disease
|March 26, 2025
概括
短睡眠时间 (SSD) 和长睡眠时间 (LSD) 与高血压 (BP) 有关. 目前的研究存在重大方法缺陷,阻碍了关于睡眠的最终结论.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 高血压研究 高血压研究
背景情况:
- 睡眠时间的建议因年龄而异,但睡眠时间短 (<7小时) 是普遍存在的.
- 短睡眠时间 (SSD) 和长睡眠时间 (LSD,>9小时) 都与不良的血压 (BP) 水平有关.
- 目前关于睡眠时间和血压的研究受限于方法上的缺陷.
研究的目的:
- 批判性地评估研究睡眠时间与血压之间的关联的研究方法.
- 发现研究设计,参与者选择,血压测量和睡眠时间评估方面的缺陷.
主要方法:
- 在PubMed的系统文献搜索睡眠时间和血压研究,包括那些在元分析中引用的研究.
- 分析的重点是确定横截面和纵向研究中常见的方法缺陷.
- 评估使用24小时门诊血压监测 (ABPM) 和客观睡眠评估 (动图) 的研究.
主要成果:
- 发现的主要缺陷包括依赖横截面数据,纳入高血压患者,单一办公室血压测量和主观睡眠回忆.
- 即使是有限的ABPM研究,尽管存在缺陷,显示异常睡眠时间和白天/夜间高血压之间的关联.
- 夜间的缩血压和浸泡模式是主要不良心血管事件的强有力的预测因素.
结论:
- 目前的证据将短时间或长时间的睡眠时间与不良血压结果联系起来,受到重大方法学限制的阻碍.
- 采用强有力的方法,如长期ABPM和正常压力人群的客观睡眠监测等进一步研究至关重要.
- 了解睡眠时间和血压之间的准确关系对于预测和管理心血管风险至关重要.
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