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Updated: May 20, 2025

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微环境细胞相互作用中的污染物 肝炎 癌症 过渡期和应用多态学分析的应用

Yulun Jian1, Yuhan Li1, Yanfeng Zhou1

  • 1School of Public Health, Center for Single-Cell Omics, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

Toxics
|March 26, 2025
PubMed
概括

环境污染物通过几个阶段驱动肝损伤:非酒精性脂肪性肝病 (NAFLD),纤维化和肝细胞癌 (HCC). 这项研究揭示了污染物机制和预防肝病的目标.

关键词:
细胞相互作用 细胞相互作用污染物的污染物是污染物.曝光物质 (exposomics) 是一种表现物质.炎症性癌症的转变变化肝脏的微环境是一个微环境.

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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