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Updated: Jul 13, 2026

In vivo Near Infrared Fluorescence NIRF Intravascular Molecular Imaging of Inflammatory Plaque, a Multimodal Approach to Imaging of Atherosclerosis
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PaAP可激活的NIR探头用于诊断,成像和发现针对植入物相关生物膜感染的小分子疗法

Kaixuan Liu1, Yang Liu1, Qinghua Wang1

  • 1State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.

Journal of medicinal chemistry
|March 26, 2025
PubMed
概括

新的成像工具可以检测植入物上的Pseudomonas aeruginosa生物膜. 一种新型化合物LY-58破坏了生物膜的形成并提高了抗生素的有效性,为治疗植入物相关感染提供了新的策略.

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相关概念视频

iChip01:24

iChip

The cultivation of environmental microorganisms has long been hindered by the inability to replicate complex native conditions in vitro. The isolation chip (iChip) addresses this limitation by facilitating the growth of previously uncultivable microorganisms through in situ incubation. Designed for high-throughput microbial cultivation, the iChip comprises hundreds of microchambers, each capable of housing a single microbial cell. These microchambers are loaded with a mixture of molten agar and...