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Updated: May 20, 2025

Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens
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与11p15.5相关的叶染色细胞瘤和偏角细胞瘤的遗传变化

Pavla Jenčová, Tatiana Vosecká, Lucie Štolová

    Endocrine-related cancer
    |March 26, 2025
    PubMed
    概括

    在11p15.5区域的变化,包括母亲的等位基因丢失,父亲的单亲异位基因分裂 (pUPD) 和父亲的等位基因增加,都与色细胞瘤和偏角细胞瘤 (PPGL) 的发展有关. 这些发现表明了新的机制,并非仅限于伪阴极性集群PPGLs.

    关键词:
    H19 H19 是一种H19病毒.KCNQ1 一个国家.在MLPA中,我们可以使用MLPA.甲基化处理的方法在pUPDPD中,我们可以帕拉格里奥马马是什么意思叶染色细胞瘤 ( pheochromocytoma) 是一种致血性细胞瘤.地区 11p15.5 地区 11p15.5

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