在低收入和中等收入国家的青少年母亲中出现黄症
Laura van der Krogt1, Alexandra Ridout1, Nicola Vousden2
1Division of Women's Health, King's College London, Women's Health Academic Centre, St Thomas' Hospital, London, United Kingdom.
PLOS global public health
|March 26, 2025
概括
在低收入和中等收入国家,青少年母亲面临着明显更高的湿风险,这是一种危险的高血压疾病. 有针对性的干预措施对于改善这个脆弱群体的结果至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 全球健康 全球健康
- 孕产妇健康 孕产妇健康
背景情况:
- 孕产妇死亡率仍然是一个关键的全球卫生问题,可预防的原因导致每天约800人死亡.
- 青少年母亲不成比例地经历了这些不良结果,特别是在低收入和中等收入国家 (LMICs).
- 高血压疾病,包括赤血症,占直接孕产妇死亡的20%,通常是可以预防的.
研究的目的:
- 量化LMIC中青春期母亲患黄昏症的高风险.
- 为了比较青少年与非青少年母亲的阴发病率和相对风险.
- 突出健康不平等导致青少年怀孕中阴.
主要方法:
- 在CRADLE计划中,对三项大型多中心研究的数据进行二次分析.
- 从常规来源和在撒哈拉以南非洲,印度和海地十个地区发现活跃病例前性收集数据.
- 与年龄较大的母亲相比,青春期母亲的黄昏症发病率和相对风险的计算.
主要成果:
- 总共分析了601,343例分娩,其中有3,098例黄昏症 (发病率为0.51%).
- 在不同地点,黄昏症的发病率有很大的差异,从每10,000次分娩中有22到142次.
- 青少年占湿病例的34%,相对于年龄较大的母亲 (p<0.0001),相对风险为1.50至3.45.
结论:
- 在被研究的LMIC中,青少年母亲面临着显著更高的黄昏症风险.
- 这一发现在各种环境中的可复制性强调了青少年母亲对健康不平等的脆弱性.
- 进一步的研究和有针对性的干预措施是必要的,以解决青春期怀孕中的黄昏症,并改善孕产妇/产前期的结果.
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