电子卫生干预对血液透析患者的有效性:系统性审查和元分析
Xu-Hua Zhou1,2, Hui Chen1,2, Weiwei Yang1,2
1Hemodialysis Center, Department of Nephrology, West China Hospital, Sichuan University, Chengdu, China.
Journal of medical Internet research
|March 26, 2025
概括
电子健康干预措施有望改善血液透析患者的生活质量和治疗坚持,同时减少焦虑和抑郁. 需要进一步高质量的试验才能得出最终的结论.
科学领域:
- 腎病學與數位健康學
背景情况:
- 电子健康干预措施正在为血液透析患者探索,但缺乏强有力的证据.
- 此前对这群人群的电子健康疗效的研究是有限的.
研究的目的:
- 对血液透析患者的电子健康干预措施的疗效进行元分析.
- 评估对生活质量,治疗坚持,焦虑和抑郁症的影响.
- 确定有效的干预组件和方法质量.
主要方法:
- 系统搜索10个随机对照试验 (RCT) 数据库,直到2024年9月.
- 包括英语和中文的eHealth对血液透析患者的RCT.
- 使用随机效应模型和GRADE用于证据质量评估的定量合成.
主要成果:
- 分析了17个带有1728名参与者的RCT,使用各种电子健康格式 (文本,视频,应用程序等). ) 的情况.
- 电子健康干预显著改善了生活质量 (低确定性),坚持 (中等确定性),减少了焦虑和抑郁 (中等确定性).
- 大多数研究在选择,性能和检测方面都存在"一些担忧"或"高风险"的偏见.
结论:
- 电子健康干预似乎对血液透析患者的生活质量,坚持和心理健康有益.
- 高质量的RCT对于更强有力的证据和可靠的结论至关重要.
相关概念视频
01:27Dialysis
244
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
244
01:22Heart Failure Drugs: Diuretics
309
Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
309
01:17Factors Affecting Renal Clearance: Renal Impairment
44
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
44
01:26Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
354
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
354
01:33Hormonal Regulation
32.8K
The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
32.8K
01:11Renal Failure: Dose Adjustments
50
In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
50