孕妇体重增加与妊娠期糖尿病风险增加有关
Sunmie Kim1, Kyungdo Han2, Su-Yeon Choi3
1Department of Obstetrics and Gynecology, Seoul National University Hospital Healthcare System Gangnam Center, Seoul National University College of Medicine, Seoul, Korea.
显著的孕期体重增加增加妊娠期糖尿病 (GDM) 的风险,即使在非肥胖妇女. 在怀孕前最大限度地减少体重增加对于预防GDM至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 孕期糖尿病 (GDM) 是怀孕期间的一个重大问题.
- 以前的研究表明,孕期体重增加和GDM风险之间存在联系.
- 本研究使用韩国国家卫生数据调查了这一关联.
研究的目的:
- 检查孕前体重变化与发展GDM的风险之间的关系.
- 评估体重增加对GDM发病率的剂量依赖影响.
- 确定特定的子组,其中这种关联更明显.
主要方法:
- 进行了一项回顾性,全国性,基于人口的队列研究.
- 分析了2015-2017年间分娩的159,798名妇女的数据.
- 妇女根据怀孕前两次健康检查之间的体重变化 (≥10%, 5-10%, -5%至 5%, -10%至 -5%, ≤-10%) 分类.
主要成果:
- 在146,363名被分析的女性中,有11,012名 (7.52%) 被诊断为GDM.
- 5-10%的体重增加与12%的GDM风险增加有关 (aOR,1.12;95% CI,1.06-1.17).
- 体重增加≥10%显示GDM风险增加了34% (aOR,1.34;95% CI,1.26-1.43),特别是在非肥胖女性中.
结论:
- 怀孕期间的体重增加表明与高GDM风险的剂量依赖关系.
- 由于体重增加而导致GDM的风险即使在没有肥胖的女性中也是显著的.
- 建议在各种体重类别中尽量减少孕前体重增加,以预防GDM.
更多相关视频
05:17Author Spotlight: Enhancing the Offspring Health in Rats with Maternal Exercise During Pregnancy
Published on: April 5, 2024
06:39Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Diabetes: Symptoms, Diagnosis, and Complications
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Psychoneuroimmunology: Diabetes and Cancer
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
