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kynurenine在小鼠中放大了四大麻素诱导的感觉运动障碍和经典的"四度"效应

Sabrine Bilel1, Giorgia Corli1, Edoardo Tiziani2

  • 1Department of Translational Medicine, Section of Legal Medicine, LTTA Center and University Center of Gender Medicine, University of Ferrara, Ferrara, Italy.

Progress in neuro-psychopharmacology & biological psychiatry
|March 26, 2025
PubMed
概括

L-kynurenine (KYN) 放大了delta-9-tetrahydrocannabinol (THC) 对小鼠感觉运动功能和行为的影响. 这表明药物动力学相互作用可能是THC诱导的损伤和精神病风险的基础.

关键词:
类大麻素 (cannabinoids) 是一种类大麻素.氨酸是什么 氨酸是什么基努瑞宁路径的通道.精神错乱是一种精神病.Δ(9) -THC代谢物的代谢物.

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