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Updated: May 20, 2025

Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions
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Published on: August 2, 2018

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缺氧诱导的NDRG1 C端多酸化会损害其瘤抑制功能,在细胞癌中

Qiang Guo1, Mei-Yu Quan2, Jingyu Zheng3

  • 1School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.

Cancer letters
|March 26, 2025
PubMed
概括

缺氧触发N-myc下游调节基因1 (NDRG1) C端多酸化,促进其降解和清细胞细胞癌 (ccRCC) 转移. 这突显了NDRG1酸化作为ccRCC进展中的治疗点.

关键词:
在EMT中,EMT是EMT.氧气过低是因为缺氧.在 NDRG1 中,一个SGK1SGK1在Ubiquitination中使用.在WNT信号传输中.

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