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Updated: May 20, 2025

Dispersion of Nanomaterials in Aqueous Media: Towards Protocol Optimization
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对八种纳米纤维化纤维素及其汉森溶解性参数的分散性研究

Zhonggeng Wang1, Luzhu Fang1, Sensen Ma1

  • 1College of Materials Science and Engineering, Henan Key Laboratory of Advanced Nylon Materials and Application, Zhengzhou University, Zhengzhou 450001, China.

International journal of biological macromolecules
|March 26, 2025
PubMed
概括

这项研究确定了纳米纤维化纤维素 (NFC) 的汉森溶解性参数 (HSP),以预测其在各种溶剂中的分散. 较小的NFC直径和更高的-COOH含量提高了分散性,指导了复合材料的材料选择.

关键词:
分散的分散性.高度服务提供者 (HSP)纳米纤维化的纤维素.度 度 度 度

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Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
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