Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

DNA Microarrays02:34

DNA Microarrays

17.1K
Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
17.1K
Ribosome Profiling02:24

Ribosome Profiling

3.4K
Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
3.4K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Integrated physiological, transcriptomic and metabolomic analysis reveal the tolerance thresholds and mechanisms of <i>Cynanchum auriculatum</i> to saline and alkaline stress.

Physiology and molecular biology of plants : an international journal of functional plant biology·2026
Same author

The metabolic change trajectory of skeletal muscle during the life cycle: arteriovenous metabolomics.

Life medicine·2026
Same author

Synergistic Engineering Assembly of Twisted Mesoporous Carbon Nanorods as Potential Lithium-Ion Battery Anodes.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Long-term metabolic-adiposity burden and cardiovascular risk: the cumTyG-WHtR in Chinese adults.

BMC cardiovascular disorders·2026
Same author

A Zinc-Coordinated Glycopolymer for Inhibiting Bacterial Toxins in Management of Acute Pneumonia.

ACS applied materials & interfaces·2026
Same author

Huanglian wendan decoction attenuates hepatic inflammation and lipogenesis via inhibition of the NF-κB/HDAC1/SREBP-1c axis.

Journal of ethnopharmacology·2026
Same journal

3DICE: Interpretable 3D Cross-Modal Learning for Drug-Target Interaction Prediction and Large-Scale Drug Discovery.

Bioinformatics (Oxford, England)·2026
Same journal

KASSPer: Kinase Active Site Structure Prediction using Protein and Ligand Language Models and Its Application to Virtual Screening.

Bioinformatics (Oxford, England)·2026
Same journal

IDR searcher: a search engine solution for public image resources.

Bioinformatics (Oxford, England)·2026
Same journal

KCFtools: Rapid alignment-free method for introgression screening and GWAS using k-mer profiles.

Bioinformatics (Oxford, England)·2026
Same journal

Meta2DB: Curated shotgun metagenomic feature sets and metadata for health state prediction.

Bioinformatics (Oxford, England)·2026
Same journal

conMItion: an R package adjusting confounding factors for associations in multi-omics.

Bioinformatics (Oxford, England)·2026
查看所有相关文章

相关实验视频

Updated: May 20, 2025

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection
09:19

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection

Published on: July 6, 2022

4.8K

在空间转录组学中用于空间变量基因识别的基准测试算法.

Xuanwei Chen1, Qinghua Ran2, Junjie Tang3

  • 1School of Mathematical Sciences, Peking University, Beijing 100871, China.

Bioinformatics (Oxford, England)
|March 26, 2025
PubMed
概括
此摘要是机器生成的。

本研究引入了一个基准框架,用于评估使用30个合成和74个现实数据集的空间基因识别算法. 它帮助科学家选择最好的工具进行空间转录分析.

更多相关视频

Isolation and Profiling of Human Primary Mesenteric Arterial Endothelial Cells at the Transcriptome Level
09:45

Isolation and Profiling of Human Primary Mesenteric Arterial Endothelial Cells at the Transcriptome Level

Published on: March 14, 2022

2.9K
Competitive Genomic Screens of Barcoded Yeast Libraries
11:59

Competitive Genomic Screens of Barcoded Yeast Libraries

Published on: August 11, 2011

18.2K

相关实验视频

Last Updated: May 20, 2025

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection
09:19

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection

Published on: July 6, 2022

4.8K
Isolation and Profiling of Human Primary Mesenteric Arterial Endothelial Cells at the Transcriptome Level
09:45

Isolation and Profiling of Human Primary Mesenteric Arterial Endothelial Cells at the Transcriptome Level

Published on: March 14, 2022

2.9K
Competitive Genomic Screens of Barcoded Yeast Libraries
11:59

Competitive Genomic Screens of Barcoded Yeast Libraries

Published on: August 11, 2011

18.2K

科学领域:

  • 基因组学就是基因组学.
  • 生物信息学是一种生物信息学.
  • 计算生物学 计算生物学

背景情况:

  • 空间转录学正在快速发展,突出了对有效的空间变量基因识别的需求.
  • 目前用于识别空间变量基因的方法缺乏标准化的基准测试,阻碍了验证和比较.
  • 这种局限性使得选择合适的算法来进行现实世界的空间转录数据分析变得更加复杂.

研究的目的:

  • 开发和介绍一个全面的基准框架,用于评估识别空间变量基因的算法.
  • 评估各种算法的性能,使用多样化的合成和现实世界数据集.
  • 引导研究人员选择最佳算法,并为空间转录组学新计算方法的开发提供信息.

主要方法:

  • 使用基准框架对空间变量基因识别算法的评估.
  • 分析了30个合成和74个现实世界的空间转录数据集.
  • 在不同数据集和生物环境中对算法性能进行系统比较.

主要成果:

  • 确定用于空间变量基因识别的最有效算法.
  • 描述不同算法的最佳应用场景.
  • 为未来的算法评估建立一个可重复的框架.

结论:

  • 拟议的基准框架有助于选择适当的空间变量基因识别算法.
  • 这种资源有助于生命科学家和生物信息学家推进空间转录基因组研究.
  • 该框架促进开发更强大,更有效的计算工具来分析空间空间数据.