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Updated: May 20, 2025

Quantification of Atherosclerosis in Mice
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升高的残留和LDL胆固醇和周围动脉疾病的风险:孟德尔的随机化研究

Benjamin Nilsson Wadström1, Maria Carolina Borges2, Anders Berg Wulff3

  • 1Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom; Department of Clinical Biochemistry, Copenhagen University Hospital-Herlev and Gentofte, Herlev, Denmark; The Copenhagen General Population Study, Copenhagen University Hospital-Herlev and Gentofte, Herlev, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Journal of the American College of Cardiology
|March 26, 2025
PubMed
概括

升高的残留胆固醇,而不仅仅是LDL胆固醇,因果性地增加了周围动脉疾病 (PAD) 的风险. 剩余胆固醇似乎是主要的驱动因素,这表明PAD预防和治疗的新治疗点.

关键词:
关键的四肢缺血症 关键的四肢缺血症脂蛋白脂酶是一种脂蛋白脂酶.下肢动脉疾病 - 下肢动脉疾病富含甘油三酸盐的脂蛋白蛋白.非常低密度的脂蛋白.

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