带有神经眼科表现的多胞膜炎呈现的神经眼科表现的eosinophilic粒状瘤
Sahar Noorani1, Ali Shah Tejani, Mingyi Chen
1Departments of Neurology (SN), Radiology (AST), Pathology (MC), Ophthalmology (MT-L), and University of Texas Southwestern Medical Center, Dallas, Texas; and Department of Ophthalmology (MT-L), University of Mississippi Medical Center, Jackson, Mississippi.
概括
带有多炎 (EGPA) 的异性粒状炎可以表现为眼球和轨道炎症. 早期诊断和类固醇节约疗法,如梅波利祖马布,对于管理这种罕见的疾病至关重要.
科学领域:
- 神经眼科神经眼科
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
背景情况:
- 带有多炎 (EGPA) 的异性粒状炎是一种罕见的全身性血管炎.
- 眼睛和轨道表现的EGPA可以是最初的呈现迹象.
研究的目的:
- 描述一个EGPA病例,呈现出单独的轨道炎症.
- 突出EGPA的诊断挑战和治疗策略.
主要方法:
- 临床病例呈现方式
- 神经眼科检查 眼神学检查
- 大脑和轨道的磁共振成像 (MRI).
- 肌肉活检 肌肉活检
- 完整的血液细胞计数与差异化.
- 用皮质类固醇和梅波利祖马治疗
主要成果:
- 患者出现了眼,视盘,以及轨道炎症.
- 核磁共振扫描显示了轨道结构的扩大和增强.
- 肌肉活检显示反应性淋巴细胞透与eosinophilia.
- 记住了外围的阳.
- 皮质类固醇治疗症状有所改善,但在停止服用后复发.
- 对EGPA的诊断得到了证实.
- 通过mepolizumab成功治疗.
结论:
- 在轨道炎症状况的差异诊断中应考虑EGPA.
- 及时诊断和适当的管理,包括类固醇节约剂,对于EGPA的良好结果至关重要.
- 眼睛和轨道干扰可能是EGPA的主要表现.
相关概念视频
Glaucoma: Overview
484
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
484
Photoreceptors and Visual Pathways
5.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
5.5K
Open Angle Glaucoma: Treatment
375
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
375


