大子周长是土耳其人口精液质量差的预测因素吗?
1Department of Histology-Embryology and IVF Clinic, Faculty of Medicine, Selcuk University, Konya, Turkey. duygudursunoglu@yahoo.com.
Reproductive sciences (Thousand Oaks, Calif.)
|March 27, 2025
概括
肥胖会对男性生育能力产生负面影响. 像子周长 (NC) 这样的新措施预测精子运动率降低,突出体脂分布.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 安德罗学与人类学
- 肥胖医学 肥胖医学
背景情况:
- 肥胖和精液质量之间的关系尚未完全理解.
- 传统的身体质量指数 (BMI) 可能不准确地反映中心脂肪.
- 中部脂肪的新型人体指数,如子周长 (NC),需要调查它们对男性生育能力的影响.
研究的目的:
- 调查各种脂肪指数的预测潜力,包括子周长 (NC),用于精液质量差.
- 评估不同肥胖测量和特定精液参数之间的关联.
主要方法:
- 一项涉及4739名年龄在17-55岁之间的男性的横截面研究.
- 基于世卫组织标准的精液参数 (度,数量,运动性,活力) 的评估.
- 人类指数的测量:BMI,腰围 (WC),部周长 (HC),腰与部比率 (WHpR),腰与身高比率 (WHtR) 和NC.
- 使用接收器运行特征 (ROC) 曲线和二进制后勤回归进行分析,并根据混因素进行调整.
主要成果:
- 精液质量较差的个人表现出更高的肥胖指数.
- 所有检查的肥胖指数都显示出降低精液参数的预测潜力.
- 在调整了混因素后,部周长 (HC) 与精子数有很强的相关性.
- 腰围 (WC) 和腰与身高比 (WHtR) 与精子活力和运动性有关.
- 腰部至部比 (WHpR) 和子周长 (NC) 显示出与快速渐进的精子运动性最强的关联.
结论:
- 肥胖严重导致男性不孕.
- 根据各种人体指数评估的身体脂肪分布的特定模式,对精子功能和不孕症标志物产生不同的影响.
- 子周长 (NC) 成为减少快速渐进的精子运动性的重要预测指标,表明它在男性不孕症中的作用.
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