视神经病监测:在全国范围的队列研究中,现实世界查实践和相关因素的变化
1Department of Pre-Medicine, College of Medicine and Biostatistics Lab, Medical Research Collaborating Center (MRCC), Hanyang University, Seoul, South Korea.
Clinical therapeutics
|March 27, 2025
概括
在现实世界中,针对乙胺醇视神经病变 (EON) 的查因患者的人口统计和临床因素而有很大差异. 需要有针对性的干预措施来改善查和预防因乙醇而导致的视力丧失.
科学领域:
- 眼科医生 眼科 眼科
- 药物监督 药物监督 药物监督
- 公共卫生 公共卫生
背景情况:
- 乙醇是结核病治疗的关键抗生素.
- 乙胺光学神经病变 (EON) 是一个严重的潜在副作用.
- 现实世界对EON的查实践没有得到很好的描述.
研究的目的:
- 调查真实世界的查实践,以探究乙醇光学神经病变 (EON).
- 确定影响EON查变异的人口和临床因素.
- 为了分析全国范围的韩国队列中的查差异.
主要方法:
- 分析了一组全国范围的119,636名韩国患者开始服用乙醇 (2015-2021年).
- 使用了国家健康保险审查和评估 (HIRA) 数据库.
- 基于患者特征和医疗保健环境的基线和随后的眼科检查率的比较.
主要成果:
- 观察到基线和随访查的显著差异.
- 年轻的患者,大都会居民和接受传染病专家治疗的人更有可能进行基线查.
- 女性,非肺结核患者和转诊中心患者的查率较低.
结论:
- 目前的视觉神经病查实践表现出显著的差异.
- 标准化指导方针和有针对性的干预措施对于改善查至关重要.
- 加强查是必要的,以防止ethambutol用户的视力损失.
更多相关视频
07:11Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
6.2K
03:47Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
Published on: November 1, 2024
126
相关概念视频
01:19Pharmacovigilance
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
01:29Therapeutic Drug Monitoring: Affecting Factors
Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.