大脑不对称及其与神经发育过程中的注意力不集中和遗传性相关
1National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA. dardo.tomasi@nih.gov.
Translational psychiatry
|March 27, 2025
概括
儿童的注意力不集中是高度遗传的,并且与背后上角 (dpSTS) 中的大脑不对称性有关. 非遗传因素可能会影响dpSTS不对称性和认知表现.
科学领域:
- 神经科学是一个神经科学.
- 遗传学 是一个遗传学.
- 发展心理学 发展心理学
背景情况:
- 遗传性和大脑不对称与注意力不集中的联系尚未完全理解.
- 大脑不对称模式在整个生命周期中保持稳定.
研究的目的:
- 为了研究大脑不对称和注意力不集中之间的关系.
- 为了检查大脑不对称和注意力不集中的遗传性.
主要方法:
- 在大型队列 (ABCD,HCP) 上利用先进的神经成像 (静止状态fMRI,形态测量).
- 对可重现的大脑不对称性模式的数据驱动指标进行分析.
主要成果:
- 在儿童 (9-10岁) 中,高度注意力不集中是61%的遗传.
- 在dpSTS中减少向左不对称性与注意力不集中有关.
- dpSTS不对称性具有较低的遗传性 (16%) 并与较低的认知表现相关.
结论:
- 不注意的遗传性是显著的,与特定的大脑不对称性有关.
- 非遗传因素可能会影响dpSTS不对称性和认知功能.
- 认知干预可能会改善大脑功能,减少注意力不集中.
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