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Updated: May 20, 2025

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功能变异的CREB3增益可以保护ALS

Salim Megat1, Christine Marques2, Marina Hernán-Godoy2

  • 1Université de Strasbourg, Inserm, Strasbourg Translational Neuroscience and Psychiatry, Inserm UMR-S 1329, Centre de Recherche en Biomédecine de Strasbourg, Strasbourg, France. salim.megat@inserm.fr.

Nature communications
|March 27, 2025
PubMed
概括

肌缩侧面硬化症 (ALS) 研究揭示了转录因子CREB3作为弹性标志物. 一种罕见的CREB3变体 (CREB3R119G) 可能降低ALS风险并减缓疾病的进展.

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